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Filtered Search Results
Medchemexpress LLC LDN-91946 | 439946-22-2 | 98.0% | 1 ML
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LDN-91946 is a potent, selective, and uncompetitive ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitor with a Ki app of 2.8 μM. It is intended for research use only. The compound is inactive against UCH-L3 at 20 μM and shows no activity against TGase 2, Papain, and Caspase-3 at 40 μM. It also exhibits no cytotoxicity in serum-starved Neuro 2A (N2A) cells at concentrations up to 0.1 mM.
- Potent, selective, and uncompetitive UCH-L1 inhibitor
- Ki app of 2.8 μM (UCH-L1)
- Inactive against UCH-L3 at 20 μM
- No activity against TGase 2, Papain, and Caspase-3 at 40 μM
- No cytotoxicity in serum-starved Neuro 2A (N2A) cells up to 0.1 mM
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Medchemexpress LLC Cathepsin G inhibitor I | 429676-93-7 | MFCD28137715 | >=99.0% | 620.63 | C36H33N2O6P | 25 MG
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Cathepsin G Inhibitor I is a selective, reversible, competitive, non-peptide inhibitor of cathepsin G with nanomolar potency (IC50 = 53 nM; Ki = 63 nM). It is provided in both solid and DMSO solution formats for use in biochemical and cell-based assays to study serine protease inhibition.
- Selective inhibition of cathepsin G (IC50 53 nM; Ki 63 nM).
- Reversible, competitive, non-peptide mechanism suitable for biochemical assays.
- Available in multiple solid quantities and solution formats for assay flexibility.
- High purity (≥99.0%) for reproducible results.
- Molecular weight 620.63 and molecular formula C36H33N2O6P.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Mutant IDH1 inhibitor | 1429180-08-4 | 99.1% | 466.58 | 50 MG
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Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with an IC50 of < 72 nM. It is used for research purposes in the treatment of diseases or disorders associated with mutant IDH proteins, including cell-proliferation disorders like cancer.
- Potent mutant IDH1 R132H inhibitor
- IC50 of < 72 nM
- Used for research purposes
- Treats diseases associated with mutant IDH proteins
- Including cell-proliferation disorders like cancer
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000287006 WNT PATHWAY INHIBITO 10MG
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LaMarKa Chemical Company Calmagite Manual (contains Ammonium Hydroxide), 4l
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Calmagite Manual (contains Ammonium Hydroxide), 4l Plastic Bottle
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LaMarKa Chemical Company Hydrochloric Acid 0.1N Methyl Red/THAM Endpoint, 4l
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Hydrochloric Acid 0.1N Methyl Red/THAM Endpoint, 4l Plastic Jug
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LaMarKa Chemical Company Acetic Acid 6% V/V, 20l
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Acetic Acid 6% V/V, 64-49-7, WT%: >5%, 20l
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LaMarKa Chemical Company Copper Sulfate 0.5M (Degassed with Helium), 4l
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Copper Sulfate 0.5M (Degassed with Helium), 4l Plastic Jug
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LaMarKa Chemical Company Reagent 77, Barium Chloride5% W/V (Neutral), 1gal
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Reagent 77, Barium Chloride5% W/V (Neutral), 1gal Plastic Bottle
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LaMarKa Chemical Company Bromothymol Blue 0.1%W/V (1gpl) (in Methanol with Sodium Hydroxide), 1l
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Bromothymol Blue 0.1%W/V (1gpl) (in Methanol with Sodium Hydroxide), 1l Plastic Bottle
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LaMarKa Chemical Company 2,2-Bipyridine, 500ml
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2,2-Bipyridine, 366-18-7, WT%: 0.8 - 1.5%, 500ml
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LaMarKa Chemical Company Xylene/Butanol 3:1 V/V, 4l
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Xylene/Butanol 3:1 V/V, 4l Amber Glass Bottle
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Medchemexpress LLC Cyclophilin inhibitor 1 | 1509904-96-4 | 99.6% | 593.67 g/mol | C31H39N5O7 | 5 MG
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Cyclophilin inhibitor 1 is a potent, orally bioavailable small-molecule inhibitor of Cyclophilin A. It binds Cyclophilin A with a reported Kd of 5 nM and shows antiviral activity against hepatitis C virus genotype 2a with an EC50 of 98 nM. The compound is supplied as a solid with high purity and is soluble in DMSO for use in biochemical and cellular studies.
- Potent Cyclophilin A inhibitor (Kd ~5 nM).
- Demonstrated anti-HCV activity (EC50 98 nM, HCV 2a).
- Reported oral bioavailability in preclinical studies.
- High purity suitable for biochemical and cellular assays.
- Soluble in DMSO; supplied as a solid for reconstitution.
- Offered in small quantities for research use.
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Apexbio Technology LLC DEET 134-62-3 1g
DEET (134-62-3) is a small-molecule antagonist targeting insect odorant receptors It is designed to disrupt molecular interactions within chemosensory pathways thereby inhibiting insect attraction and biting behavior DEET exerts its biological activity primarily through interference with insect odorant receptors In in vitro and behavioral assays DEET demonstrates inhibitory activity with variable IC50 values reported for receptor modulation and insect behavioral responses Based on these pharmacological properties DEET holds research potential in evaluating insect chemoreception and vector-host interactions relevant to the transmission of pathogens such as Zika virus malaria parasites West Nile virus Lyme disease-causing bacteria and Rocky Mountain spotted fever agents
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IMEB, Inc Diff Stain Solution A, (Fixative), 32 oz
32 oz Diff Stain Solution A (Fixative) Also available for purchase: Diff Stain Kit- 6 pc kit.
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